Time-Dependent Vascular Effects of Endocannabinoids Mediated by Peroxisome Proliferator-Activated Receptor Gamma (PPAR𝛾)

The aim of the present study was to examine whether endocannabinoids cause PPAR𝛾-mediated vascular actions. Functional vascular studies were carried out in rat aortae. Anandamide and N-arachidonoyl-dopamine (NADA), but not palmitoylethanolamide, caused significant vasorelaxation over time (2 hours...

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Bibliographic Details
Main Authors: Saoirse E. O'Sullivan, David A. Kendall, Michael D. Randall
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/425289