Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts.
During blastocyst formation the segregation of the inner cell mass (ICM) and trophectoderm is governed by the mutually antagonistic effects of the transcription factors Oct4 and Cdx2. Evidence indicates that suppression of Oct4 expression in the trophectoderm is mediated by Cdx2. Nonetheless, the un...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-05-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2868905?pdf=render |