A Model of Cytotoxic Dose-Response Nonlinearities Arising from Adaptive Cell Inventory Management in Tissues
Why do low-level exposures to environmental toxins often elicit over-compensating responses that reduce risk to an organism? Conversely, if these responses improve health, why wait for an environmental challenge to trigger them? This paper presents a mathematical modeling framework that addresses bo...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2005-10-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.2203/dose-response.003.04.005 |