Sonic Hedgehog—‘Jack-of-All-Trades’ in Neural Circuit Formation
As reflected by the term morphogen, molecules such as Shh and Wnts were identified based on their role in early development when they instruct precursor cells to adopt a specific cell fate. Only much later were they implicated in neural circuit formation. Both in vitro and in vivo studies indicated...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-02-01
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Series: | Journal of Developmental Biology |
Subjects: | |
Online Access: | http://www.mdpi.com/2221-3759/5/1/2 |