Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution

Retroelement—Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution

<b>Background:</b> Retroelements (REs) are transposable elements occupying ~40% of the human genome that can regulate genes by providing transcription factor binding sites (TFBS). RE-linked TFBS profile can serve as a marker of gene transcriptional regulation evolution. This approach all...

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Bibliographic Details
Main Authors: Daniil Nikitin, Andrew Garazha, Maxim Sorokin, Dmitry Penzar, Victor Tkachev, Alexander Markov, Nurshat Gaifullin, Pieter Borger, Alexander Poltorak, Anton Buzdin
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Human genome evolution
transcription factor
retrotransposons
molecular pathways
gene ontology
ChIP-seq
omics approach in genetics
Online Access:https://www.mdpi.com/2073-4409/8/2/130

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