Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells

X-linked dystonia-parkinsonism (XDP) is a hereditary neurodegenerative disorder involving a progressive loss of striatal medium spiny neurons. The mechanisms underlying neurodegeneration are not known, in part because there have been few cellular models available for studying the disease. The XDP ha...

Full description

Bibliographic Details
Main Authors: Naoto Ito, William T. Hendriks, Jyotsna Dhakal, Christine A. Vaine, Christina Liu, David Shin, Kyle Shin, Noriko Wakabayashi-Ito, Marisela Dy, Trisha Multhaupt-Buell, Nutan Sharma, Xandra O. Breakefield, D. Cristopher Bragg
Format: Article
Language:English
Published: The Company of Biologists 2016-04-01
Series:Disease Models & Mechanisms
Subjects:
X-linked dystonia-parkinsonism
Induced pluripotent stem cells
TAF1
Online Access:http://dmm.biologists.org/content/9/4/451

Internet

http://dmm.biologists.org/content/9/4/451

Similar Items