Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer

Differential intratumoral distributions of CD8 and CD163 immune cells as prognostic biomarkers in breast cancer

Abstract Background Tumor immune cell infiltrates are essential in hindering cancer progression and may complement the TNM classification. CD8+ and CD163+ cells have prognostic impact in breast cancer but their spatial heterogeneity has not been extensively explored in this type of cancer. Here, the...

Full description

Bibliographic Details
Main Authors: Sotirios P. Fortis, Michael Sofopoulos, Nectaria N. Sotiriadou, Christoforos Haritos, Christoforos K. Vaxevanis, Eleftheria A. Anastasopoulou, Nicole Janssen, Niki Arnogiannaki, Alexandros Ardavanis, Graham Pawelec, Sonia A. Perez, Constantin N. Baxevanis
Format: Article
Language:English
Published: BMJ Publishing Group 2017-04-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Breast cancer
Tumor infiltration
CD8
CD163
Immunoscoring
Prognostic signature
Online Access:http://link.springer.com/article/10.1186/s40425-017-0240-7

Internet

http://link.springer.com/article/10.1186/s40425-017-0240-7

Similar Items