YKL-40 acts as an angiogenic factor to promote tumor angiogenesis

A secreted glycoprotein YKL-40 also named chitinase-3-like-1 is normally expressed by multiple cell types such as macrophages, chondrocytes, and vascular smooth muscle cells. However, a prominently high level of YKL-40 was found in a wide spectrum of human diseases including cancers and chronic infl...

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Bibliographic Details
Main Author: Rong eShao
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00122/full