YKL-40 acts as an angiogenic factor to promote tumor angiogenesis
A secreted glycoprotein YKL-40 also named chitinase-3-like-1 is normally expressed by multiple cell types such as macrophages, chondrocytes, and vascular smooth muscle cells. However, a prominently high level of YKL-40 was found in a wide spectrum of human diseases including cancers and chronic infl...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-05-01
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Series: | Frontiers in Physiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00122/full |