TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
Controlled cell death can be an efficient anti-viral strategy, but also leads to tissue damage and needs to be balanced. Oyler-Yaniv et al. combine mathematical modelling and microscopy to show that exposure to TNF in response to viral infection causes cells to tune their speed-vs-accuracy trade-off...
Main Authors: | Jennifer Oyler-Yaniv, Alon Oyler-Yaniv, Evan Maltz, Roy Wollman |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-23195-9 |
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