Tailored surface silica nanoparticles for blood-brain barrier penetration: Preparation and in vivo investigation

Surface modified fluorescent silica nanoparticle derivatives (Ru@SNPs), namely, glucose (Glu) and glucose-poly (ethylene glycol) methyl ether amine (Glu-PEG) coated SNPs were designed and tested for their ability to penetrate the blood-brain barrier (BBB) in mice brain. The new obtained nanoparticle...

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Bibliographic Details
Main Authors: B.I. Tamba, V. Streinu, G. Foltea, A.N. Neagu, G. Dodi, M. Zlei, A. Tijani, C. Stefanescu
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535218300777