Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study
Objectives: Trimethoprim (TMP)/sulfamethoxazole (SMX) has consistently demonstrated great interindividual variability. Therapeutic drug monitoring may be used to optimize dosing. Optimal peak SMX concentration has been proposed as 100 to 150 μg/mL. The objective of our work was to determine the succ...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Current Therapeutic Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0011393X14000204 |