Modeling Lung Derecruitment in VILI Due to Fluid-Occlusion: The Role of Emergent Behavior

Ventilator-induced lung injury (VILI) is driven by the processes of volutrauma and atelectrauma, which can act synergistically to compromise the blood-gas barrier. We have postulated that this synergy arises through a rich-get-richer mechanism whereby atelectrauma causes holes to form in the blood-g...

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Bibliographic Details
Main Authors: Vitor Mori, Bradford J. Smith, Bela Suki, Jason H. T. Bates
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.542744/full