Synthesis, In Vitro Profiling, and In Vivo Efficacy Studies of a New Family of Multitarget Anti-Alzheimer Compounds

Synthesis, In Vitro Profiling, and In Vivo Efficacy Studies of a New Family of Multitarget Anti-Alzheimer Compounds

Simultaneous modulation of several targets or pathological events with a key pathogenic role is<br />a promising strategy to tackle thus far difficult-to-cure or incurable multifactorial diseases [...]

Bibliographic Details
Main Authors:	Francisco Javier Pérez-Areales, María Garrido, Ester Aso, Manuela Bartolini, Angela De Simone, Alba Espargaró, Tiziana Ginex, Raimon Sabate, Belén Pérez, Vincenza Andrisano, Francisco Javier Luque, Isidro Ferrer, Francisco Ciruela, Angel Messeguer, Diego Muñoz-Torrero
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Proceedings
Subjects:	multitarget compounds multitarget-directed ligands acetylcholinesterase inhibitors butyrylcholinesterase inhibitors BACE-1 inhibitors, anti-aggregating agents antioxidant properties brain permeability in vivo efficacy studies.
Online Access:	https://www.mdpi.com/2504-3900/22/1/71

Description
Summary:	Simultaneous modulation of several targets or pathological events with a key pathogenic role is<br />a promising strategy to tackle thus far difficult-to-cure or incurable multifactorial diseases [...]
ISSN:	2504-3900