Synthesis, In Vitro Profiling, and In Vivo Efficacy Studies of a New Family of Multitarget Anti-Alzheimer Compounds

Synthesis, In Vitro Profiling, and In Vivo Efficacy Studies of a New Family of Multitarget Anti-Alzheimer Compounds

Simultaneous modulation of several targets or pathological events with a key pathogenic role is<br />a promising strategy to tackle thus far difficult-to-cure or incurable multifactorial diseases [...]

Bibliographic Details
Main Authors: Francisco Javier Pérez-Areales, María Garrido, Ester Aso, Manuela Bartolini, Angela De Simone, Alba Espargaró, Tiziana Ginex, Raimon Sabate, Belén Pérez, Vincenza Andrisano, Francisco Javier Luque, Isidro Ferrer, Francisco Ciruela, Angel Messeguer, Diego Muñoz-Torrero
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Proceedings
Subjects:
multitarget compounds
multitarget-directed ligands
acetylcholinesterase inhibitors
butyrylcholinesterase inhibitors
BACE-1 inhibitors, anti-aggregating agents
antioxidant properties
brain permeability
in vivo efficacy studies.
Online Access:https://www.mdpi.com/2504-3900/22/1/71

Internet

https://www.mdpi.com/2504-3900/22/1/71

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