Complex coordinated extracellular metabolism: Acid phosphatases activate diluted human leukocyte proteins to generate energy flow as NADPH from purine nucleotide ribose

Complex coordinated extracellular metabolism: Acid phosphatases activate diluted human leukocyte proteins to generate energy flow as NADPH from purine nucleotide ribose

Complex metabolism is thought to occur exclusively in the crowded intracellular environment. Here we report that diluted enzymes from lysed human leukocytes produce extracellular energy. Our findings involve two pathways: the purine nucleotide catabolic pathway and the pentose phosphate pathway, whi...

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Bibliographic Details
Main Authors: John B. Hibbs Jr., Zdenek Vavrin, James E. Cox
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Redox Biology
Subjects:
Extracellular metabolism
Redox regulation
Human leukocytes
Leukocyte and human prostate acid phosphatases
Transaldolase
Glutathione reductase
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171630012X

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http://www.sciencedirect.com/science/article/pii/S221323171630012X

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