Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21

<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood.</p> <p>Methods</p> <p>We used oligonucleot...

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Bibliographic Details
Main Authors: Zigman Warren B, Silverman Wayne, Schupf Nicole, Salas Martha, Guo Meirong, Li Chi-Ming, Husain Sameera, Warburton Dorothy, Thaker Harshwardhan, Tycko Benjamin
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/7/24