A new charge-tagged proline-based organocatalyst for mechanistic studies using electrospray mass spectrometry

A new 4-hydroxy-L-proline derivative with a charged 1-ethylpyridinium-4-phenoxy substituent has been synthesized with the aim of facilitating mechanistic studies of proline-catalyzed reactions by ESI mass spectrometry. The charged residue ensures a strongly enhanced ESI response compared to neutral...

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Bibliographic Details
Main Authors: J. Alexander Willms, Rita Beel, Martin L. Schmidt, Christian Mundt, Marianne Engeser
Format: Article
Language:English
Published: Beilstein-Institut 2014-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.211