Evaluation of Collagen Fibers, MMP2, MMP9, 8-OHdG and Apoptosis in the Aorta of Ovariectomized LDL Knockout Mice Submitted to Aerobic Exercise

Evaluation of Collagen Fibers, MMP2, MMP9, 8-OHdG and Apoptosis in the Aorta of Ovariectomized LDL Knockout Mice Submitted to Aerobic Exercise

Abstract Background: In menopause, there is greater cellular exposure to oxidative stress, related to the decreased antioxidative effects of estrogen. These metabolic changes favor the progression of cardiovascular diseases, such as atherosclerosis. Abnormal function of the aorta - the most importa...

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Main Authors: Laura Beatriz M. Maifrino, Nathalia E. A. de Lima, Mara R. Marques, Clever G. Cardoso, Lidiane B. de Souza, Tabata de Carvalho Tomé, Hananiah Tardivo Quintana, Flavia de Oliveira, Beatriz da Costa Aguiar Alves Reis, Fernando Luiz Affonso Fonseca
Format: Article
Language:English
Published: Sociedade Brasileira de Cardiologia (SBC) 2018-12-01
Series:Arquivos Brasileiros de Cardiologia
Subjects:
Rats
Cardiovascuar Diseases
Menopause
Fibrillar Collagens/analysis
Ovariectomy
Exercise
Cholesterol, LDL
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005021102&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005021102&lng=en&tlng=en

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