The impact of high density receptor clusters on VEGF signaling

Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding of the bivalent VEGF ligand to the membrane-bound receptors (VEGFR), which in turn stimulates receptor dimerization. Herein, we discuss experi...

Full description

Bibliographic Details
Main Authors: Ye Chen, Christopher Short, Ádám M. Halász, Jeremy S. Edwards
Format: Article
Language:English
Published: Open Publishing Association 2013-08-01
Series:Electronic Proceedings in Theoretical Computer Science
Online Access:http://arxiv.org/pdf/1309.0868v1