Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells

Notch2 signal is required for the maintenance of canine hemangiosarcoma cancer stem cell-like cells

Abstract Background Hemangiosarcoma (HSA) is a malignant tumor derived from endothelial cells which usually shows poor prognosis due to its high invasiveness, metastatic rate and severe hemorrhage from tumor ruptures. Since the pathogenesis of HSA is not yet complete, further understanding of its mo...

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Bibliographic Details
Main Authors: Keisuke Aoshima, Yuki Fukui, Kevin Christian Montecillo Gulay, Ochbayar Erdemsurakh, Atsuya Morita, Atsushi Kobayashi, Takashi Kimura
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Veterinary Research
Subjects:
Cancer stem cell-like cells
Hemangiosarcoma
Notch2
Oncology
Tumor Biology
Online Access:http://link.springer.com/article/10.1186/s12917-018-1624-8

Internet

http://link.springer.com/article/10.1186/s12917-018-1624-8

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