Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

Abstract In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they do not revert the disease progression and re...

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Bibliographic Details
Main Authors: Shashank Vasudevan, Janko Kajtez, Ada‐Ioana Bunea, Ana Gonzalez‐Ramos, Tania Ramos‐Moreno, Arto Heiskanen, Merab Kokaia, Niels B. Larsen, Alberto Martínez‐Serrano, Stephan S. Keller, Jenny Emnéus
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201902011