CD8+ T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation [version 1; referees: 2 approved]
Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell–based vaccines. Thus far, CD8 T-cell vaccination strategies have had limited success therape...
Main Authors: | Gabriela Cosma, Laurence Eisenlohr |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-04-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-508/v1 |
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