CD8+ T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation [version 1; referees: 2 approved]

Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell–based vaccines. Thus far, CD8 T-cell vaccination strategies have had limited success therape...

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Bibliographic Details
Main Authors: Gabriela Cosma, Laurence Eisenlohr
Format: Article
Language:English
Published: F1000 Research Ltd 2018-04-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-508/v1