ZG16 regulates PD-L1 expression and promotes local immunity in colon cancer

CRC is a heterogeneous disease due to global molecular alterations, including mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H). Immunotherapy has achieved durable responses in a subset of patients with dMMR-MSI-H metastatic CRC. It has been showed that Loss of ZG16 is hig...

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Bibliographic Details
Main Authors: Hui Meng, Yi Ding, Enjie Liu, Wencai Li, Liang Wang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304952