Paracrine Neuroprotective Effects of Neural Stem Cells on Glutamate-Induced Cortical Neuronal Cell Excitotoxicity

Paracrine Neuroprotective Effects of Neural Stem Cells on Glutamate-Induced Cortical Neuronal Cell Excitotoxicity

Purpose: Glutamate is a major excitatory neurotransmitter in mammalian central nervous system. Excessive glutamate releasing overactivates its receptors and changes calcium homeostasis that in turn leads to a cascade of intracellular events causing neuronal degeneration. In current study, we used ne...

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Bibliographic Details
Main Authors: Mohammad Hossein Geranmayeh, Ali Baghbanzadeh, Abbas Barin, Jamileh Salar-Amoli, Mohammad Mehdi Dehghan, Reza Rahbarghazi, Hassan Azari
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2015-11-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Glutamate
Neural stem cells
Neurons
Primary cell culture
Cell viability
Rat
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-5-515.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-5-515.pdf

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