Structural and chemical profiling of the human cytosolic sulfotransferases.

Structural and chemical profiling of the human cytosolic sulfotransferases.

The human cytosolic sulfotransfases (hSULTs) comprise a family of 12 phase II enzymes involved in the metabolism of drugs and hormones, the bioactivation of carcinogens, and the detoxification of xenobiotics. Knowledge of the structural and mechanistic basis of substrate specificity and activity is...

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Main Authors: Abdellah Allali-Hassani, Patricia W Pan, Ludmila Dombrovski, Rafael Najmanovich, Wolfram Tempel, Aiping Dong, Peter Loppnau, Fernando Martin, Janet Thornton, Aled M Edwards, Alexey Bochkarev, Alexander N Plotnikov, Masoud Vedadi, Cheryl H Arrowsmith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0050097

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https://doi.org/10.1371/journal.pbio.0050097

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