Recombinant protein production associated growth inhibition results mainly from transcription and not from translation

Abstract Background Recombinant protein production can be stressful to the host organism. The extent of stress is determined by the specific properties of the recombinant transcript and protein, by the rates of transcription and translation, and by the environmental conditions encountered during the...

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Bibliographic Details
Main Authors: Zhaopeng Li, Ursula Rinas
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-020-01343-y