Dynamic prediction based on variability of a longitudinal biomarker

Abstract Background Tacrolimus is given post-kidney transplant to suppress the immune system, and the amount of drug in the body is measured frequently. Higher variability over time may be indicative of poor drug adherence, leading to more adverse events. It is important to account for the variation...

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Bibliographic Details
Main Authors: Kristen R. Campbell, Rui Martins, Scott Davis, Elizabeth Juarez-Colunga
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-021-01294-x