EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus

EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus

Destabilization of a non-enveloped virus generates a membrane transport-competent viral particle. Here we probe polyomavirus SV40 endoplasmic reticulum (ER)-to-cytosol membrane transport, a decisive infection step where destabilization initiates this non-enveloped virus for membrane penetration. We...

Full description

Bibliographic Details
Main Authors: Parikshit Bagchi, Takamasa Inoue, Billy Tsai
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
protein stabilization
membrane transport
viral entry
Online Access:https://elifesciences.org/articles/21470

Internet

https://elifesciences.org/articles/21470

Similar Items