Sumoylation of DNA-bound transcription factor Sko1 prevents its association with nontarget promoters.

Sequence-specific transcription factors (TFs) represent one of the largest groups of proteins that is targeted for SUMO post-translational modification, in both yeast and humans. SUMO modification can have diverse effects, but recent studies showed that sumoylation reduces the interaction of multipl...

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Bibliographic Details
Main Authors: Veroni S Sri Theivakadadcham, Benjamin G Bergey, Emanuel Rosonina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6392331?pdf=render