Sumoylation of DNA-bound transcription factor Sko1 prevents its association with nontarget promoters.
Sequence-specific transcription factors (TFs) represent one of the largest groups of proteins that is targeted for SUMO post-translational modification, in both yeast and humans. SUMO modification can have diverse effects, but recent studies showed that sumoylation reduces the interaction of multipl...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6392331?pdf=render |