Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer

Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer

Tao Ren,1–3,* Jinlu Shan,1,* Mengxia Li,1 Yi Qing,1 Chengyuan Qian,4 Guangjie Wang,5 Qing Li,1,3 Guoshou Lu,1 Chongyi Li,1 Yu Peng,1 Hao Luo,1 Shiheng Zhang,1 Yuxing Yang,1 Yi Cheng,1 Dong Wang,1 Shu-Feng Zhou31Cancer Center, Daping Hospital and Research Institute of Surgery, Third Militar...

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Bibliographic Details
Main Authors: Ren T, Shan J, Li M, Qing Y, Qian C, Wang G, Li Q, Lu G, Li C, Peng Y, Luo H, Zhang S, Yang Y, Cheng Y, Wang D, Zhou SF
Format: Article
Language:English
Published: Dove Medical Press 2015-06-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/small-molecule-bh3-mimetic-and-pan-bcl-2-inhibitor-at-101-enhances-the-peer-reviewed-article-DDDT

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http://www.dovepress.com/small-molecule-bh3-mimetic-and-pan-bcl-2-inhibitor-at-101-enhances-the-peer-reviewed-article-DDDT

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