Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site.

Transglutaminase2 (TG2) is a multi-functional protein involved in various cellular processes, including apoptosis, differentiation, wound healing, and angiogenesis. The malfunction of TG2 causes many human disease including inflammatory disease, celiac disease, neurodegenerative diseases, tissue fib...

Full description

Bibliographic Details
Main Authors: Tae-Ho Jang, Dong-Sup Lee, Kihang Choi, Eui Man Jeong, In-Gyu Kim, Young Whan Kim, Jung Nyeo Chun, Ju-Hong Jeon, Hyun Ho Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4156391?pdf=render