Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome

Linarin ameliorates innate inflammatory response in an experimental dry eye model via modulation of the NLRP3 inflammasome

Objective: To investigate the effect and mechanism of linarin (LA) in an experimental dry eye model Methods: LA or vehicle was applied in two dry eye models: an in vitro hyperosmotic stress model and an in vivo desiccating stress (DS) murine model. The viability of human corneal epithelial cells (HC...

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Bibliographic Details
Main Authors: Chen Mei, Li Jie, Peng Jun, Huang Yu, Ouyang Weijie, Liu Xiaoqing, Shen Zhibin, Li Changdong, Wang Yi, Peng Qinghua
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-03-01
Series:Digital Chinese Medicine
Subjects:
Linarin
dry eye disease
NLRP3 inflammasome
ocular surface
innate inflammatory response
Online Access:http://www.sciencedirect.com/science/article/pii/S2589377721000069

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http://www.sciencedirect.com/science/article/pii/S2589377721000069

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