Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor
<p>Abstract</p> <p>Background</p> <p>Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications. The endothelial cells are the first cells targeted by hyperglycemia. The mechanism of endothelial injury by high glucose is sti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-08-01
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| Series: | Cardiovascular Diabetology |
| Online Access: | http://www.cardiab.com/content/4/1/12 |