TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice

TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice

Tripartite motif-containing protein 31 (TRIM31), an E3 ubiquitin ligase of the tripartite motif family, plays an important role in the innate immune response. It can reduce the activity of the nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3) infl...

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Bibliographic Details
Main Authors: Jing Cheng, Fei Xue, Meng Zhang, Cheng Cheng, Lei Qiao, Jing Ma, Wenhai Sui, Xingli Xu, Chengjiang Gao, Panpan Hao, Yun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Physiology
Subjects:
TRIM31
glucose metabolism
insulin resistance
gut microbiota
inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00024/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00024/full

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