The Impact of Normalization Methods on RNA-Seq Data Analysis

High-throughput sequencing technologies, such as the Illumina Hi-seq, are powerful new tools for investigating a wide range of biological and medical problems. Massive and complex data sets produced by the sequencers create a need for development of statistical and computational methods that can tac...

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Bibliographic Details
Main Authors: J. Zyprych-Walczak, A. Szabelska, L. Handschuh, K. Górczak, K. Klamecka, M. Figlerowicz, I. Siatkowski
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/621690