Dimethyl sulfoxide (DMSO) exacerbates cisplatin-induced sensory hair cell death in zebrafish (Danio rerio).

Dimethyl sulfoxide (DMSO) exacerbates cisplatin-induced sensory hair cell death in zebrafish (Danio rerio).

Inner ear sensory hair cells die following exposure to aminoglycoside antibiotics or chemotherapeutics like cisplatin, leading to permanent auditory and/or balance deficits in humans. Zebrafish (Danio rerio) are used to study drug-induced sensory hair cell death since their hair cells are similar in...

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Bibliographic Details
Main Authors: Phillip M Uribe, Melissa A Mueller, Julia S Gleichman, Matthew D Kramer, Qi Wang, Martha Sibrian-Vazquez, Robert M Strongin, Peter S Steyger, Douglas A Cotanche, Jonathan I Matsui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3562182?pdf=render

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http://europepmc.org/articles/PMC3562182?pdf=render

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