Claudin-12 is not required for blood–brain barrier tight junction function

Claudin-12 is not required for blood–brain barrier tight junction function

Abstract Background The blood–brain barrier (BBB) ensures central nervous system (CNS) homeostasis by strictly controlling the passage of molecules and solutes from the bloodstream into the CNS. Complex and continuous tight junctions (TJs) between brain endothelial cells block uncontrolled paracellu...

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Bibliographic Details
Main Authors: Mariana Castro Dias, Caroline Coisne, Pascale Baden, Gaby Enzmann, Lillian Garrett, Lore Becker, Sabine M. Hölter, German Mouse Clinic Consortium, Martin Hrabě de Angelis, Urban Deutsch, Britta Engelhardt
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Fluids and Barriers of the CNS
Subjects:
Claudin-12
Tight junctions
Blood–brain barrier
Experimental autoimmune encephalomyelitis
Online Access:http://link.springer.com/article/10.1186/s12987-019-0150-9

Internet

http://link.springer.com/article/10.1186/s12987-019-0150-9

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