Cryopreservation Preserves Cell-Type Composition and Gene Expression Profiles in Bone Marrow Aspirates From Multiple Myeloma Patients

Cryopreservation Preserves Cell-Type Composition and Gene Expression Profiles in Bone Marrow Aspirates From Multiple Myeloma Patients

Single-cell RNA sequencing reveals gene expression differences between individual cells and also identifies different cell populations that are present in the bulk starting material. To obtain an accurate assessment of patient samples, single-cell suspensions need to be generated as soon as possible...

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Bibliographic Details
Main Authors: Duojiao Chen, Mohammad I. Abu Zaid, Jill L. Reiter, Magdalena Czader, Lin Wang, Patrick McGuire, Xiaoling Xuei, Hongyu Gao, Kun Huang, Rafat Abonour, Brian A. Walker, Yunlong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Genetics
Subjects:
cryopreservation
multiple myeloma
single-cell RNA sequencing
DMSO
bone marrow aspirate
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.663487/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.663487/full

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