A Novel System for Identification of Inhibitors of Rift Valley Fever Virus Replication

A Novel System for Identification of Inhibitors of Rift Valley Fever Virus Replication

Rift Valley fever virus (RVFV) is a human and livestock pathogen endemic to sub-Saharan Africa. We have developed a T7-dependent system for the efficient production of RVFV-like particles (RVF-VLPs) based on the virulent ZH-501 strain of RVFV. The RVF-VLPs are capable of performing a single round of...

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Bibliographic Details
Main Authors: Mary E. Piper, Sonja R. Gerrard
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:Viruses
Subjects:
Rift Valley fever
virus-like particle
RNA virus
Bunyaviridae
Phlebovirus
minigenome
antivirals
Online Access:http://www.mdpi.com/1999-4915/2/3/731/

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http://www.mdpi.com/1999-4915/2/3/731/

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