Targeted cytotoxic therapy kills persisting HIV infected cells during ART.

Targeted cytotoxic therapy kills persisting HIV infected cells during ART.

Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dynamics of ART-induced reductions in viral RNA (vRNA...

Full description

Bibliographic Details
Main Authors: Paul W Denton, Julie M Long, Stephen W Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D Snyder, Katherine Perkey, Nancie M Archin, Shailesh K Choudhary, Kuo Yang, Michael G Hudgens, Ira Pastan, Ashley T Haase, Angela D Kashuba, Edward A Berger, David M Margolis, J Victor Garcia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3887103?pdf=render

Internet

http://europepmc.org/articles/PMC3887103?pdf=render

Similar Items