Comparison of different methods to overexpress large genes

Comparison of different methods to overexpress large genes

Gain-of-function of very large transgene constructs can lead to genetic perturbations, providing researchers with the alternative of a powerful tool to identify pathway components which remain undetected when using traditional loss-of-function analysis. To promote longer-term expression, various sys...

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Bibliographic Details
Main Authors: Aline Lisie Ramos, Fernanda Soares Niemann, Adriana Silva Santos Duarte, Karla Priscila Ferro, Irene Santos, Carolina Louzão Bigarella, Antonio Filareto, Sara Teresinha Olalla Saad
Format: Article
Language:English
Published: PAGEPress Publications 2018-10-01
Series:Journal of Biological Research
Subjects:
Gene Overexpression
Large Genes
Transgene Integration
Transposon System
Lentiviral System
DNA Transfer Systems
Online Access:https://www.pagepressjournals.org/index.php/jbr/article/view/7249

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https://www.pagepressjournals.org/index.php/jbr/article/view/7249

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