Prominent Hyperproinsulinemia in a Middle Age Patient

Introduction: Insulin is synthesized in the β-cells from preproinsulin. Preproinsulin becomes proinsulin after leaving the signal peptide. Proinsulin is separated into C-peptide and insulin by 2 enzymes. Hyperproinsulinemia is suspected to be a pancreatic β-cell defect that is augmented by the incre...

Full description

Bibliographic Details
Main Authors: Hiroshi Yoshino, Kyoko Kawakami, Kei Yoshino, Gen Yoshino
Format: Article
Language:English
Published: SAGE Publishing 2021-09-01
Series:Clinical Medicine Insights: Case Reports
Online Access:https://doi.org/10.1177/11795476211042241