A critical role for NF2 and the Hippo pathway in branching morphogenesis

A critical role for NF2 and the Hippo pathway in branching morphogenesis

Branching morphogenesis is essential for the formation of most epithelial organs. Here, the authors show that Neurofibromatosis 2 (NF2), the Hippo pathway kinases LATS1 and LATS2, and the transcriptional co-activators YAP and TAZ control tip identity, RET signalling and branching morphogenesis in th...

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Bibliographic Details
Main Authors: Antoine Reginensi, Leonie Enderle, Alex Gregorieff, Randy L. Johnson, Jeffrey L. Wrana, Helen McNeill
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12309

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https://doi.org/10.1038/ncomms12309

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