New strategies for Leptospira vaccine development based on LPS removal.

New strategies for Leptospira vaccine development based on LPS removal.

Pathogenic spirochetes from genus Leptospira are etiologic agents of leptospirosis. Cellular vaccines against Leptospira infection often elicit mainly response against the LPS antigen of the serovars present in the formulation. There is no suitable protein candidate capable of replacing whole-cell v...

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Bibliographic Details
Main Authors: Fabiana Lauretti-Ferreira, Paloma L D Silva, Naiara M Alcântara, Bruna F Silva, Isabele Grabher, Gisele O Souza, Erika Nakajima, Milena A Akamatsu, Silvio A Vasconcellos, Patricia A E Abreu, Eneas Carvalho, Elizabeth A L Martins, Paulo L Ho, Josefa B da Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230460

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https://doi.org/10.1371/journal.pone.0230460

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