Transplantation of autologous bone marrow-derived mesenchymal stem cells under arthroscopic surgery with microfracture versus microfracture alone for articular cartilage lesions in the knee: A multicenter prospective randomized control clinical trial

Introduction: To investigate the efficacy of the transplantation of autologous bone marrow-derived mesenchymal stem cells (BMSCs) under arthroscopy with microfracture (MFX) compared with microfracture alone. Methods: Eleven patients with a symptomatic articular cartilage defect of the knee were incl...

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Main Authors: Yusuke Hashimoto, Yohei Nishida, Shinji Takahashi, Hiroaki Nakamura, Hisashi Mera, Kaori Kashiwa, Shinichi Yoshiya, Yusuke Inagaki, Kota Uematsu, Yasuhito Tanaka, Shigeki Asada, Masao Akagi, Kanji Fukuda, Yoshiya Hosokawa, Akira Myoui, Naosuke Kamei, Masakazu Ishikawa, Nobuo Adachi, Mitsuo Ochi, Shigeyuki Wakitani
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Regenerative Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320419300616