Improvements of renal lesions and function by angiotensin and endothelin receptor antagonism in nitric oxide-deficient rats

In previous studies, we have observed that antagonism of angiotensin or endothelin receptors prevented the development of nephroangio- and glomerulo-sclerosis during hypertension by inhibiting collagen I gene synthesis, through a mechanism independent of systemic haemodynamics. The present study inv...

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Bibliographic Details
Main Authors: Jean-Jacques Boffa, Ying Lu, Jean-Claude Dussaule, Christos Chatziantoniou
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2001-03-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/14703203010020013701