Improvements of renal lesions and function by angiotensin and endothelin receptor antagonism in nitric oxide-deficient rats
In previous studies, we have observed that antagonism of angiotensin or endothelin receptors prevented the development of nephroangio- and glomerulo-sclerosis during hypertension by inhibiting collagen I gene synthesis, through a mechanism independent of systemic haemodynamics. The present study inv...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2001-03-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/14703203010020013701 |