Effects of CTLA4-Ig on human monocytes

Effects of CTLA4-Ig on human monocytes

Abstract Background Abatacept, a CTLA4-Ig fusion protein attenuates T cell activation by inhibiting the CD80/86-CD28 costimulatory pathway that is required for the proper T cell activation and thus displays beneficial effects in the treatment of rheumatoid arthritis (RA). Although some studies have...

Full description

Bibliographic Details
Main Authors: Toshihiro Tono, Satoko Aihara, Takayuki Hoshiyama, Yoshiyuki Arinuma, Tatsuo Nagai, Shunsei Hirohata
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Inflammation and Regeneration
Subjects:
Abatacept
Monocytes
Apoptosis
Costimulation molecules
Online Access:http://link.springer.com/article/10.1186/s41232-017-0054-5

Internet

http://link.springer.com/article/10.1186/s41232-017-0054-5

Similar Items