Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

<p>Abstract</p> <p>Background</p> <p>Diabetes is associated with changes in myocardial stress-response pathways and is recognized as an independent risk factor for cardiac remodeling. Using spontaneously diabetic Goto Kakizaki rats as a model of type 2 DM we investigate...

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Main Authors: Kytö Ville, Kaheinen Petri, Raivio Johanna, Merasto Saara, Forstén Hanna, Louhelainen Marjut, Vahtola Erik, Tikkanen Ilkka, Levijoki Jouko, Mervaala Eero
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Cardiovascular Diabetology
Online Access:http://www.cardiab.com/content/9/1/5