Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Summary: Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration. Here, the significance of Tgf-β signaling fo...

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Bibliographic Details
Main Authors: Poonam Sharma, Shivangi Gupta, Mansi Chaudhary, Soumitra Mitra, Bindia Chawla, Mohammad Anwar Khursheed, Navnoor Kaur Saran, Rajesh Ramachandran
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219305632

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http://www.sciencedirect.com/science/article/pii/S2589004219305632

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